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CS-W001157 4
Total: USD 88.00

2-Iodo-N,N-dimethylaniline

  • CAS No. 698-02-2

  • Cat. No. CS-0654844
  • Molecule weight247.08
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Iodo-N,N-dimethylaniline|CS-0654844

Structure of 698-02-2

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General Information

  • CAS No. 698-02-2
  • Cat. No. CS-0654844
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀IN
  • Molecular Weight 247.08
  • Synonym(s) None
  • SMILES CN(C)C1=CC=CC=C1I

Description

2-Iodo-N,N-dimethylaniline delivers a reactive iodine handle for cross-coupling applications, featuring a dimethylamino group that enhances electron density at the aromatic ring. This bench-stable reagent enables efficient Pd-catalyzed transformations under standard conditions.

Application

2-Iodo-N,N-dimethylaniline serves as a versatile aryl iodide building block in cross-coupling reactions, enabling efficient C–C bond formation under Pd-catalyzed conditions. The dimethylamino group enhances reactivity while maintaining bench stability and facilitating purification via chromatography. Its ortho-iodo substitution supports regioselective transformations in the synthesis of functionalized biaryls and heterocyclic scaffolds common in medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   2.3572
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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