Lot numbers can be found on the outside label of a product:
2-Bromo-4-fluoronitrobenzene
-
CAS No. 700-36-7
- Cat. No. CS-D1760
- Purity≥97%
- MDL No.MFCD00792441
*For research and further manufacturing use only, not for direct human use.
Structure of 700-36-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 700-36-7
- Cat. No. CS-D1760
- Purity ≥97%
- MDL No. MFCD00792441
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₃BrFNO₂
- Molecular Weight 220.00
- Synonym(s) 2-Bromo-4-fluoro-1-nitrobenzene
- SMILES O=[N+](C1=CC=C(F)C=C1Br)[O-]
Description
2-Bromo-4-fluoronitrobenzene is a highly reactive aryl halide featuring complementary electrophilic sites for cross-coupling and nucleophilic substitution. The para-fluoro group enables selective displacement under mild conditions, while the ortho-bromo moiety facilitates palladium-catalyzed coupling reactions. This bifunctional architecture supports efficient access to complex aromatic scaffolds in pharmaceutical and agrochemical synthesis.
Application
2-Bromo-4-fluoronitrobenzene serves as a versatile building block in cross-coupling chemistry and heterocycle synthesis, enabling efficient construction of biaryl and functionalized aromatic scaffolds. Its complementary halogenation pattern—bromine at C2 and fluorine at C4—facilitates selective metalation and transition-metal-catalyzed transformations. The molecule exhibits excellent bench stability and compatibility with palladium-catalyzed coupling protocols, offering predictable reactivity and straightforward purification.
Synthesis
-
Route1
-
371-40-4 - ~99%
-
In-stock
700-36-7
References
-
Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh Patent: US2008/300242 A1, 2008 ; Location in patent: Page/Page column 62 ; US 20080300242 A1
-
-
Route2
-
In-stock
1003-98-1 - ~90%
-
In-stock
700-36-7
References
-
Beugelmans, Rene; Chbani, Mohamed Bulletin de la Societe Chimique de France, 1995 , vol. 132, p. 306 - 313
-
-
Route3
-
In-stock
1073-06-9 - ~75%
-
In-stock
700-36-7
References
-
Schlosser, Manfred; Ginanneschi, Assunta; Leroux, Frederic European Journal of Organic Chemistry, 2006 , # 13 p. 2956 - 2969
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 43.14
- LogP 2.4964
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-Bromo-4-fluoronitrobenzene sigma2-Bromo-4-fluoronitrobenzene manufacturer2-Bromo-4-fluoronitrobenzene price2-Bromo-4-fluoronitrobenzene structure2-Bromo-4-fluoronitrobenzene SDSbuy 2-Bromo-4-fluoronitrobenzene2-Bromo-4-fluoronitrobenzene supplier2-Bromo-4-fluoronitrobenzene uses2-Bromo-4-fluoronitrobenzene molecular weightprice of 2-Bromo-4-fluoronitrobenzene2-Bromo-4-fluoronitrobenzene chemical name formula of 2-Bromo-4-fluoronitrobenzene