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Structure of 7035-09-8
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5-Chloro-2-methoxybenzaldehyde features a chlorine atom at the 5-position and a methoxy group at the 2-position, creating a highly electron-deficient aromatic ring. This configuration enhances reactivity in nucleophilic addition and transition-metal-catalyzed coupling reactions. The aldehyde functionality enables direct incorporation into complex molecular architectures under mild conditions.
5-Chloro-2-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of bioactive heterocycles via Ullmann-type couplings and Friedel-Crafts reactions. Its ortho-methoxy and meta-chloro substituents provide favorable electronic modulation and steric control, while the aldehyde functionality offers direct access to hydrazones, imines, and reductive amination products. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: