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Structure of 705-24-8
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4,6-Dichloro-2-(trifluoromethyl)pyrimidine is a bench-stable heterocyclic building block featuring two chlorine substituents at electron-deficient positions and a strongly electron-withdrawing trifluoromethyl group. This combination enables selective nucleophilic substitution reactions, facilitating the rapid assembly of complex pyrimidine derivatives in medicinal chemistry and agrochemical synthesis.
4,6-Dichloro-2-(trifluoromethyl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles. Its orthogonal reactivity allows selective functionalization at C4 and C6 positions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2922
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Class : 8 (6.1)
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Packing Group : Ⅱ
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Hazard Statements : H301-H314
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Precautionary Statements : P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: