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Structure of 7149-75-9
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4-Chloro-3-methylaniline is a chlorinated aniline derivative featuring a methyl group at the meta position relative to the amino function. This substitution pattern imparts enhanced electron density at the aromatic ring, facilitating electrophilic coupling reactions. The compound exhibits good bench stability and solubility in common organic solvents, enabling straightforward integration into synthetic sequences for pharmaceutical intermediates and agrochemical building blocks.
4-Chloro-3-methylaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted anilines via standard coupling reactions. Its ortho-methyl group enhances metabolic stability and modulates electronic properties, while the chloro substituent provides a handle for palladium-catalyzed functionalization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable, multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: