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Structure of 443-89-0
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2-Fluoro-6-methylaniline features a fluorinated aromatic ring paired with a methyl group at the para position, delivering enhanced electron density and improved metabolic stability. This configuration enables efficient incorporation into pharmaceutical intermediates and advanced materials. The compound exhibits excellent solubility in common organic solvents and maintains stability under standard bench conditions.
2-Fluoro-6-methylaniline serves as a valuable building block for pharmaceutical and agrochemical synthesis, offering regioselective functionalization via its ortho-fluoro and para-methyl substituents. The fluorine atom enables bioisosteric replacement and enhances metabolic stability, while the aniline handle facilitates direct coupling reactions and electrophilic aromatic substitution. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses involving amide formation, Suzuki coupling, or heterocycle construction.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H302-H315-H318-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: