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Structure of 89831-40-3
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3,4-Dimethyl-1H-pyrazole-5-carboxylic acid features a rigid pyrazole core with strategically positioned methyl groups that enhance solubility and metabolic stability. The carboxylic acid moiety enables direct conjugation or derivatization in medicinal chemistry applications. This compound serves as a bioisostere for phenyl or other heterocyclic systems in drug discovery, offering improved physicochemical properties.
3,4-Dimethyl-1H-pyrazole-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical research. Its pyrazole core provides structural rigidity and hydrogen-bonding capacity, while the carboxylic acid enables direct derivatization via amide, ester, or acyl chloride formation. The methyl substituents enhance metabolic stability and modulate lipophilicity, offering favorable properties for lead optimization. This compound exhibits good bench stability and facilitates purification through standard recrystallization or chromatography techniques.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: