Lot numbers can be found on the outside label of a product:
(4-Chloro-2-fluorophenyl)methanamine
-
CAS No. 72235-57-5
- Cat. No. CS-0094798
- Purity≥98%
- MDL No.MFCD06212852
*For research and further manufacturing use only, not for direct human use.
Structure of 72235-57-5
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 72235-57-5
- Cat. No. CS-0094798
- Purity ≥98%
- MDL No. MFCD06212852
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₇ClFN
- Molecular Weight 159.59
- Synonym(s) 4-Chloro-2-fluorobenzylamine
- SMILES NCC1=CC=C(Cl)C=C1F
Description
(4-Chloro-2-fluorophenyl)methanamine is a fluorinated arylalkylamine featuring a chloro and fluoro substituent in the para- and ortho-positions relative to the methylene group. This electron-deficient aromatic scaffold enhances metabolic stability and enables direct incorporation into bioactive molecules. The primary amine functionality supports facile derivatization, making it a valuable intermediate for pharmaceuticals and agrochemicals.
Application
(4-Chloro-2-fluorophenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated arylamines through standard amine coupling and electrophilic substitution reactions. Its ortho-fluoro and para-chloro substituents provide enhanced metabolic stability and tunable electronic properties, while the primary amine group facilitates straightforward derivatization. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows in API development.
Synthesis
-
Route1
-
536761-10-1 - ~%
-
In-stock
72235-57-5
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 13 p. 3463 - 3468
-
-
Route2
-
In-stock
61072-56-8 - ~%
-
In-stock
72235-57-5
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 13 p. 3463 - 3468
-
-
Route3
-
In-stock
56456-49-6 - ~%
-
In-stock
72235-57-5
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 13 p. 3463 - 3468
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS05
|
|
Signal Word : Danger
|
UN#: 3265
|
|
Class : 8
|
Packing Group : Ⅲ
|
|
Hazard Statements : H314
|
|
|
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 26.02
- LogP 1.9378
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- (4-Chloro-2-fluorophenyl)methanamine sigma(4-Chloro-2-fluorophenyl)methanamine manufacturer(4-Chloro-2-fluorophenyl)methanamine price(4-Chloro-2-fluorophenyl)methanamine structure(4-Chloro-2-fluorophenyl)methanamine SDSbuy (4-Chloro-2-fluorophenyl)methanamine(4-Chloro-2-fluorophenyl)methanamine supplier(4-Chloro-2-fluorophenyl)methanamine uses(4-Chloro-2-fluorophenyl)methanamine molecular weightprice of (4-Chloro-2-fluorophenyl)methanamine(4-Chloro-2-fluorophenyl)methanamine chemical name formula of (4-Chloro-2-fluorophenyl)methanamine