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CS-W001157 4
Total: USD 88.00

Boc-Aeg-OEt

  • CAS No. 72648-80-7

  • Cat. No. CS-0197392
  • Purity≥98%
  • MDL No.MFCD00672310

*For research and further manufacturing use only, not for direct human use.

Boc-Aeg-OEt|CS-0197392

Structure of 72648-80-7

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General Information

  • CAS No. 72648-80-7
  • Cat. No. CS-0197392
  • Purity ≥98%
  • MDL No. MFCD00672310
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂N₂O₄
  • Molecular Weight 246.30
  • Synonym(s) None
  • SMILES CCOC(CNCCNC(OC(C)(C)C)=O)=O

Description

Ethyl 2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)acetate features a protected amine handle flanked by an ethyl ester and a secondary amine, enabling seamless incorporation into peptide synthesis workflows. This bench-stable, moisture-tolerant building block facilitates efficient coupling reactions under standard conditions.

Application

Ethyl 2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)acetate serves as a versatile bifunctional building block for peptide and peptidomimetic synthesis, enabling efficient incorporation of aminoethyl side chains. The protected amine group offers orthogonal reactivity, while the ester functionality supports subsequent transformations such as hydrolysis or coupling reactions. Its bench-stable nature and compatibility with standard deprotection protocols facilitate streamlined synthetic workflows in medicinal chemistry and API development.

Synthesis

  • Route1
    • In-stock
      NH2-C2-NH-Boc|CS-B0430
      57260-73-8
    • null|null
      105-36-2
    • ~93%
    • In-stock
      Boc-Aeg-OEt|CS-0197392
      72648-80-7

    References

    • Fader; Boyd; Tsantrizos Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3372 - 3379
  • Route2
    • In-stock
      NH2-C2-NH-Boc|CS-B0430
      57260-73-8
    • null|null
      64805-08-9
    • ~%
    • In-stock
      Boc-Aeg-OEt|CS-0197392
      72648-80-7

    References

    • Cooper, Daniel C.; Suggs, J. William Tetrahedron Letters, 2012 , vol. 53, # 51 p. 6943 - 6945
  • Route3

    References

    • Douat-Casassus, Celine; Marchand-Geneste, Nathalie; Diez, Elisabeth; Gervois, Nadine; Jotereau, Francine; Quideau, Stephane Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1598 - 1609

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   76.66
  • LogP   0.6638
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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