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Structure of 73177-33-0
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2-Methyl-1H-indole-6-carboxylic acid features a sterically hindered indole core with a carboxylic acid group at the 6-position, enabling direct conjugation in medicinal chemistry scaffolds. The methyl substituent enhances metabolic stability while maintaining solubility under standard conditions. This derivative serves as a key building block for bioactive molecule synthesis.
2-Methyl-1H-indole-6-carboxylic acid serves as a versatile building block for the synthesis of indole-based pharmaceuticals and agrochemicals. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions under standard conditions. The methyl group at the 2-position enhances metabolic stability and modulates electronic properties, while the indole core provides a robust scaffold for medicinal chemistry optimization. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: