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Structure of 7359-14-0
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This ortho-hydroxyaryl aldehyde features a strategically positioned iodine atom and methoxy group, enabling direct functionalization in cross-coupling reactions. The phenolic hydroxyl and aldehyde moieties offer dual reactivity for downstream conjugation, while the electron-withdrawing iodide enhances electrophilicity at the aromatic ring. Stable under standard handling conditions, this compound serves as a key building block for bioactive molecule synthesis.
2-Hydroxy-5-iodo-3-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The ortho-hydroxyl group facilitates chelation in transition metal catalysis, while the iodide acts as a reliable coupling handle. Its methoxy and aldehyde functionalities offer orthogonal reactivity for sequential transformations, supporting modular synthesis of complex heterocyclic scaffolds under standard bench conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: