3-Fluoro-L-tyrosine

Name: 3-Fluoro-L-tyrosine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 7423-96-3
Cat. No. CS-0157119
Purity≥97%
MDL No.MFCD00002607

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 7423-96-3

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Description

3-Fluoro-L-tyrosine integrates a fluorinated aromatic ring into a biologically compatible amino acid scaffold, enabling site-specific incorporation into proteins via genetic code expansion. This analog supports the study of protein dynamics and structure-function relationships in live systems, offering enhanced metabolic stability and resistance to enzymatic degradation compared to native tyrosine.

Application

3-Fluoro-L-tyrosine serves as a bioisosteric analog of L-tyrosine, enabling site-specific incorporation into peptides to probe protein structure-function relationships. Its fluorinated aromatic ring enhances metabolic stability and modulates electronic properties, facilitating studies in enzyme kinetics and receptor binding. The compound exhibits excellent bench stability, tolerates standard peptide coupling conditions, and simplifies purification via its distinct chromatographic profile.

General Information

CAS No. 7423-96-3
Cat. No. CS-0157119
Purity ≥97%
MDL No. MFCD00002607
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀FNO₃
Molecular Weight 199.18
Synonym(s) None
SMILES C1=CC(=C(C=C1C[C@@H](C(=O)O)N)F)O

Computational Chemistry Data

TPSA 83.55
LogP 0.4857
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids non-Proteinogenic Amino Acids

Biochemistry Biochemicals and Reagents Pharmaceutical Research Reagents Contrast Medium Ingredients

Biochemistry Pharmaceutical Development and Drug Discovery Research Pharmaceutical Research Reagents Contrast Medium Ingredients

Key Words

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3-Fluoro-L-tyrosine

CAS No. 7423-96-3

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