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Structure of 74290-69-0
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5-Bromo-6-methylpyrazin-2-amine features a brominated pyrazine core with a methyl group at the 6-position and an amino substituent at the 2-position, enabling direct functionalization in late-stage diversification. The electron-deficient pyrazine ring facilitates coupling reactions under mild conditions, while the methyl and bromo groups provide steric and electronic control for selective transformations. This compound serves as a key scaffold in medicinal chemistry for kinase inhibitors and bioactive heterocycles.
5-Bromo-6-methylpyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of complex heterocyclic scaffolds. The bromine atom facilitates efficient functionalization via Suzuki, Stille, or Negishi coupling, while the pyrazine core provides a rigid, electron-deficient platform suitable for target-oriented synthesis. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07,GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: