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Structure of 749223-61-8
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6-Methoxy-1H-indazol-5-amine features a methoxy-substituted indazole core with a primary amine at the 5-position, offering enhanced solubility and electron-donating character. This scaffold integrates readily into bioactive molecules, particularly in kinase inhibitor design and fluorescent probe development, due to its planar structure and favorable hydrogen-bonding capacity.
6-Methoxy-1H-indazol-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive indazoline scaffolds. The methoxy group enhances solubility and modulates electronic properties, while the primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions. Its stability under standard reaction conditions and compatibility with diverse functional groups make it a practical choice for synthesizing kinase inhibitors and other heterocyclic drug candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: