3'-Deoxy-3'-fluoroadenosine

Name: 3'-Deoxy-3'-fluoroadenosine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 75059-22-2
Cat. No. CS-0022620
Purity≥98%
MDL No.MFCD20134043

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 75059-22-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 75059-22-2
Cat. No. CS-0022620
Purity ≥98%
MDL No. MFCD20134043
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₂FN₅O₃
Molecular Weight 269.24
Synonym(s) None
SMILES OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1F

Description

3'-Deoxy-3'-fluoroadenosine features a fluorine atom at the 3' position, replacing the hydroxyl group to enhance metabolic stability. This modification impedes phosphorylation and prevents chain elongation, making it a potent inhibitor of viral polymerases. The compound integrates into nucleic acid chains during replication, halting further extension due to the absence of a 3'-OH. Its electron-withdrawing fluorine substituent increases resistance to enzymatic degradation. Used in antiviral research, particularly against retroviruses and hepatitis B.

Application

3'-Deoxy-3'-fluoroadenosine serves as a valuable nucleoside analog for probing ribose conformation and enzyme substrate specificity in antiviral and anticancer research. Its 3'-fluoro substitution confers enhanced metabolic stability while maintaining compatibility with standard phosphorylation pathways, enabling direct incorporation into oligonucleotide synthesis workflows. The compound functions as a key building block for site-specific modification of RNA analogs and supports efficient coupling reactions under mild conditions.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 119.31
LogP -1.0028
H_Acceptors 8
H_Donors 3
Rotatable_Bonds 2

Other Classifications

Life Science Nucleosides & Nucleotides Halogen-modified Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

Key Words

3'-Deoxy-3'-fluoroadenosine sigma3'-Deoxy-3'-fluoroadenosine manufacturer3'-Deoxy-3'-fluoroadenosine price3'-Deoxy-3'-fluoroadenosine structure3'-Deoxy-3'-fluoroadenosine SDSbuy 3'-Deoxy-3'-fluoroadenosine3'-Deoxy-3'-fluoroadenosine supplier3'-Deoxy-3'-fluoroadenosine uses3'-Deoxy-3'-fluoroadenosine molecular weightprice of 3'-Deoxy-3'-fluoroadenosine3'-Deoxy-3'-fluoroadenosine chemical name formula of 3'-Deoxy-3'-fluoroadenosine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3'-Deoxy-3'-fluoroadenosine

CAS No. 75059-22-2

Recommended Products