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Structure of 75154-68-6
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(S)-Methyl 1-tritylaziridine-2-carboxylate is a chiral aziridine building block featuring a trityl-protected nitrogen and a methyl ester functional group. This configuration enables stereoselective ring-opening reactions in asymmetric synthesis, where the trityl group provides robust protection against racemization. The molecule's stability under standard conditions facilitates handling and integration into complex molecular architectures.
(S)-Methyl 1-tritylaziridine-2-carboxylate serves as a stereocontrolled building block for the synthesis of chiral β-amino acid derivatives and aziridine-containing heterocycles. The trityl group provides exceptional stability and facilitates purification, while the aziridine ring enables regioselective ring-opening reactions with nucleophiles under mild conditions. This reagent functions effectively in peptide-like scaffold construction and is compatible with common protecting group strategies, making it valuable for medicinal chemistry campaigns requiring enantiopure nitrogen-containing motifs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: