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Structure of 288101-48-4
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This boronate ester features a 2,4-difluorophenyl moiety paired with a tetramethyl-substituted dioxaborolane ring, delivering enhanced stability and compatibility in Suzuki-Miyaura coupling reactions. The electron-withdrawing fluorine substituents improve reactivity while maintaining bench-stable handling characteristics under standard conditions.
2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its tetramethyl-substituted dioxaborolane ring enhances air and moisture stability while maintaining high reactivity with aryl halides and pseudohalides. The 2,4-difluorophenyl moiety provides orthogonal functionalization potential and is commonly found in bioactive heterocycles, enabling efficient construction of complex pharmaceutical scaffolds under mild conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: