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CS-W001157 4
Total: USD 88.00

m-PEG8-NHS ester

  • CAS No. 756525-90-3

  • Cat. No. CS-0031584
  • Purity≥98%
  • MDL No.MFCD13184969

*For research and further manufacturing use only, not for direct human use.

m-PEG8-NHS ester|CS-0031584

Structure of 756525-90-3

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General Information

  • CAS No. 756525-90-3
  • Cat. No. CS-0031584
  • Purity ≥98%
  • MDL No. MFCD13184969
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₃₉NO₁₂
  • Molecular Weight 509.54
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

Description

m-PEG8-NHS ester enables efficient conjugation in aqueous media, combining the stability of a bench-stable NHS ester with the solubility and biocompatibility of a PEG8 spacer. This reagent facilitates site-specific labeling of primary amines in peptides, proteins, and biomolecules, streamlining bioconjugation workflows without compromising functional group integrity.

Application

m-PEG8-NHS ester serves as a versatile, water-soluble coupling reagent for amine functionalization in bioconjugation and polymer chemistry. Its eight-ethylene glycol spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester group enables efficient reaction with primary amines under physiological conditions. Ideal for labeling proteins, peptides, and oligonucleotides, it offers excellent stability, ease of purification, and compatibility with standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   137.52
  • LogP   -0.2537
  • H_Acceptors   12
  • H_Donors   0
  • Rotatable_Bonds   25

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