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Structure of 761440-26-0
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1-(3-Methoxy-4-nitrophenyl)-4-methylpiperazine features a nitro-substituted aromatic ring paired with a sterically hindered piperazine core, enabling robust coupling in late-stage functionalization. The methoxy group enhances solubility and modulates electron density, while the methylated piperazine offers improved metabolic stability and nucleophilicity under standard conditions.
1-(3-Methoxy-4-nitrophenyl)-4-methylpiperazine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and reduction protocols. The nitro group facilitates selective reduction to an amine, while the methoxy substituent enhances solubility and modulates electronic properties. Bench-stable and compatible with common purification methods, it functions effectively in multi-step synthesis workflows for targeted compound libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: