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CS-W001157 4
Total: USD 88.00

Ethyl 2-(trans-4-aminocyclohexyl)acetate hydrochloride

  • CAS No. 76308-26-4

  • Cat. No. CS-0008597
  • Purity≥97%
  • MDL No.MFCD16660366
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(trans-4-aminocyclohexyl)acetate hydrochloride|CS-0008597

Structure of 76308-26-4

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Description

Ethyl 2-(trans-4-aminocyclohexyl)acetate hydrochloride is a bench-stable, moisture-tolerant amine derivative featuring a rigid trans-cyclohexyl scaffold. This configuration enhances stereochemical control in synthetic applications, enabling efficient coupling reactions and facilitating incorporation into bioactive molecules requiring defined spatial orientation.

Application

Ethyl 2-(trans-4-aminocyclohexyl)acetate hydrochloride serves as a versatile building block for medicinal chemistry and process development, enabling direct access to functionalized cyclohexyl scaffolds. The trans-configured amine exhibits enhanced stability and predictable stereochemistry, facilitating efficient coupling reactions and derivatization. Its hydrochloride salt form improves solubility and handling, supporting robust performance in standard synthetic workflows including amidation, alkylation, and reductive amination.

General Information

  • CAS No. 76308-26-4
  • Cat. No. CS-0008597
  • Purity ≥97%
  • MDL No. MFCD16660366
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀ClNO₂
  • Molecular Weight 221.72
  • Synonym(s) trans-2-(4-Aminocyclohexyl)acetic Acid Ethyl Ester Hydrochloride
  • SMILES O=C(OCC)C[C@@H]1CC[C@@H](N)CC1.Cl

Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.8789
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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