(2-Methylthiazol-4-yl)methanol

Name: (2-Methylthiazol-4-yl)methanol
Brand: ChemScene
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CAS No. 76632-23-0
Cat. No. CS-0045367
Purity≥95%
MDL No.MFCD08703637

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(2-Methylthiazol-4-yl)methanol|CS-0045367

Structure of 76632-23-0

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Description

(2-Methylthiazol-4-yl)methanol features a thiazole ring bearing a methyl group at the 2-position and a hydroxymethyl substituent at the 4-position, delivering a bench-stable, moisture-tolerant scaffold for synthetic diversification. This functionalized heterocycle integrates readily into bioactive molecule design, particularly in medicinal chemistry applications where electron-rich aromatic systems enhance target engagement.

Application

(2-Methylthiazol-4-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds through standard functional group transformations. Its benzylic alcohol functionality facilitates oxidation to the aldehyde or carboxylic acid, while the adjacent methylthiazole ring provides a stable, electron-deficient heterocyclic core. The compound exhibits excellent bench stability and compatibility with common coupling reactions, supporting its use in modular synthesis of bioactive molecules and process-scale intermediates.

General Information

CAS No. 76632-23-0
Cat. No. CS-0045367
Purity ≥95%
MDL No. MFCD08703637
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₇NOS
Molecular Weight 129.18
Synonym(s) (2-Methyl-1,3-thiazol-4-yl)methanol
SMILES OCC1=CSC(C)=N1

Computational Chemistry Data

TPSA 33.12
LogP 0.94382
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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(2-Methylthiazol-4-yl)methanol

CAS No. 76632-23-0

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