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Structure of 766557-02-2
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6-Chloro-1H-indole-3-carboxylic acid integrates a chlorine substituent at the 6-position of the indole core, enhancing electronic properties for synthetic applications. This bench-stable carboxylic acid derivative serves as a key building block in medicinal chemistry and materials science, enabling direct coupling reactions without protection.
6-Chloro-1H-indole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into indole-based scaffolds common in kinase inhibitors and CNS-active compounds. The carboxylic acid group facilitates straightforward amide coupling, esterification, or derivatization under standard conditions. Its chloro substituent at the 6-position provides moderate electron-withdrawing character and enhances metabolic stability, while maintaining bench stability and compatibility with diverse reaction environments.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: