2-Amino-4,6-dimethylpyrimidine

Name: 2-Amino-4,6-dimethylpyrimidine
Brand: ChemScene
Availability: InStock
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CAS No. 767-15-7
Cat. No. CS-W001985
Purity≥97%
MDL No.MFCD00006102

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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2-Amino-4,6-dimethylpyrimidine|CS-W001985

Structure of 767-15-7

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Description

2-Amino-4,6-dimethylpyrimidine features a pyrimidine core with amino and methyl substituents enabling versatile integration into pharmaceutical scaffolds. The para-amino group enhances nucleophilicity, while the symmetric dimethyl substitution provides steric shielding and improved metabolic stability. This compound serves as a key building block in heterocyclic synthesis, particularly for kinase inhibitors and antiviral agents.

Application

2-Amino-4,6-dimethylpyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to pyrimidine-based scaffolds. Its well-defined reactivity supports direct functionalization at the amino and methyl positions, facilitating C–N and C–C coupling reactions under standard conditions. The compound exhibits excellent bench stability and ease of purification, making it ideal for use in multi-step syntheses and high-throughput screening campaigns.

General Information

CAS No. 767-15-7
Cat. No. CS-W001985
Purity ≥97%
MDL No. MFCD00006102
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₉N₃
Molecular Weight 123.16
Synonym(s) Acetylacetoneguanidine
SMILES Cc1cc(C)nc(n1)N

Computational Chemistry Data

TPSA 51.8
LogP 0.67564
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

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2-Amino-4,6-dimethylpyrimidine

CAS No. 767-15-7

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