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Structure of 769-21-1
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This 5-chloro-2,3-dihydrobenzofuran-3-amine features a chlorinated dihydrobenzofuran core with a primary amine at the 3-position, offering enhanced solubility and reactivity in synthetic transformations. The electron-withdrawing chlorine substituent modulates electronic density, enabling selective coupling reactions in medicinal chemistry and materials science applications.
5-Chloro-2,3-dihydrobenzofuran-3-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through palladium-catalyzed couplings and electrophilic functionalization. Its bench-stable structure features a reactive amine group with moderate nucleophilicity and excellent compatibility with common protecting groups. The chloro substituent facilitates downstream cross-coupling reactions, while the dihydrobenzofuran scaffold provides structural rigidity relevant to kinase inhibitor and CNS-targeted compound development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: