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Structure of 77249-34-4
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4-Fluoro-2,3-dimethylphenol features a fluorine atom at the para position relative to the phenolic hydroxyl, combined with methyl groups at adjacent ortho positions. This substitution pattern imparts enhanced lipophilicity and metabolic stability, making it valuable for medicinal chemistry applications. The compound exhibits improved solubility in organic solvents and maintains bench-stable performance under standard conditions.
4-Fluoro-2,3-dimethylphenol serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds through standard electrophilic substitution and coupling reactions. Its ortho-methyl groups provide steric control and enhance metabolic stability, while the phenolic hydroxyl facilitates derivatization via etherification or esterification. The molecule exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: