Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(1S,2S)-2-Fluorocyclopropanecarboxylic acid

  • CAS No. 127199-14-8

  • Cat. No. CS-0029963
  • Purity≥97%
  • MDL No.MFCD19237459
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(1S,2S)-2-Fluorocyclopropanecarboxylic acid|CS-0029963

Structure of 127199-14-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

This fluorinated cyclopropanecarboxylic acid features a strained three-membered ring with stereocontrolled fluorine incorporation, delivering enhanced metabolic stability and conformational rigidity. The (1S,2S) configuration imparts distinct stereoelectronic properties, making it valuable for probing bioactive molecule scaffolds in medicinal chemistry and as a chiral building block in asymmetric synthesis.

Application

(1S,2S)-2-Fluorocyclopropanecarboxylic acid serves as a stable, enantiomerically pure building block for the synthesis of fluorinated cyclopropane-containing molecules. Its constrained ring structure imparts distinct conformational rigidity, enabling precise spatial presentation of functional groups in medicinal chemistry applications. The carboxylic acid functionality facilitates straightforward derivatization via amide, ester, or acyl chloride formation, while the fluorine atom enhances metabolic stability and modulates electronic properties. This compound exhibits excellent bench stability and is compatible with standard coupling reactions, making it a reliable scaffold for targeted molecular design.

General Information

  • CAS No. 127199-14-8
  • Cat. No. CS-0029963
  • Purity ≥97%
  • MDL No. MFCD19237459
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅FO₂
  • Molecular Weight 104.08
  • Synonym(s) (1S,2S)-2-Fluorocyclopropanecarboxylic acid; (cis)-2-fluorocyclopropanecarboxylic acid Relative stereochemistry
  • SMILES O=C([C@H]1[C@@H](F)C1)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.429
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 127199-14-8 sigma127199-14-8 manufacturer127199-14-8 price127199-14-8 structure127199-14-8 SDSbuy 127199-14-8127199-14-8 supplier127199-14-8 uses127199-14-8 molecular weightprice of 127199-14-8127199-14-8 chemical name formula of 127199-14-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label