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Structure of 77510-50-0
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(R)-3-Hydroxypyrrolidin-2-one is a stereochemically defined heterocyclic scaffold featuring a hydroxyl group at the C3 position and a lactam functionality. This configuration imparts enhanced solubility and metabolic stability, enabling direct integration into bioactive molecules. The compound serves as a key chiral building block in medicinal chemistry, particularly for peptidomimetics and CNS-targeted therapeutics.
(R)-3-Hydroxypyrrolidin-2-one serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to pyrrolidine-based pharmacophores. Its well-defined stereochemistry and stable lactam framework facilitate selective functionalization at the C3 hydroxyl group, supporting downstream transformations such as etherification, esterification, and glycosylation. The compound exhibits excellent bench stability and compatibility with standard purification methods, making it ideal for use in multi-step synthesis of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: