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Structure of 777-12-8
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6-(Trifluoromethyl)benzo[d]thiazol-2-amine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the thiazole nitrogen provides a strong hydrogen-bond acceptor site. This scaffold integrates readily into kinase inhibitors and fluorescent probes due to its planar structure and favorable solubility under standard conditions.
6-(Trifluoromethyl)benzo[d]thiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the amine functionality facilitates direct coupling reactions. The molecule exhibits excellent bench stability and compatibility with standard synthetic transformations, making it ideal for parallel library synthesis and lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H300-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: