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CS-W001157 4
Total: USD 88.00

HOOCCH2O-PEG4-CH2COOH

  • CAS No. 77855-75-5

  • Cat. No. CS-0087653
  • Purity≥97%
  • MDL No.MFCD29079379
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

HOOCCH2O-PEG4-CH2COOH|CS-0087653

Structure of 77855-75-5

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Description

This bifunctional PEG linker features carboxylic acid termini on both ends, enabling straightforward conjugation to amine-containing biomolecules or surfaces. The four-ethylene glycol repeat units provide enhanced solubility and reduced non-specific binding, making it ideal for bioconjugation applications in drug delivery and diagnostic development.

Application

HOOCCH₂O-PEG₄-CH₂COOH serves as a bifunctional, water-soluble linker ideal for conjugation and macrocyclic scaffold construction. The terminal carboxylic acid groups enable efficient amide coupling under standard conditions, while the polyether chain provides enhanced solubility and conformational flexibility. This structure facilitates reliable purification and stability in aqueous environments, making it well-suited for applications in peptide-drug conjugates, polymer chemistry, and bioconjugation workflows.

General Information

  • CAS No. 77855-75-5
  • Cat. No. CS-0087653
  • Purity ≥97%
  • MDL No. MFCD29079379
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂O₉
  • Molecular Weight 310.30
  • Synonym(s) None
  • SMILES O=C(O)COCCOCCOCCOCCOCC(O)=O

Computational Chemistry Data

  • TPSA   120.75
  • LogP   -0.7614
  • H_Acceptors   7
  • H_Donors   2
  • Rotatable_Bonds   16

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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