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Structure of 78056-39-0
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3,4-Difluoro-6-nitroaniline features a nitro group at the para position relative to an amino functionality, flanked by fluorine substituents that enhance electron withdrawal and metabolic stability. This combination imparts strong electrophilic character, enabling efficient coupling in C–N bond formation reactions. The molecule exhibits bench-stable behavior under standard conditions and integrates readily into advanced synthetic intermediates for pharmaceutical and agrochemical applications.
3,4-Difluoro-6-nitroaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of fluorinated arylamine motifs into complex scaffolds. Its reactivity profile supports nucleophilic substitution, palladium-catalyzed coupling, and reduction to the corresponding amine for further functionalization. The compound exhibits good bench stability and facilitates purification via standard crystallization or chromatographic methods, making it well-suited for iterative synthetic campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: