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Structure of 782495-18-5
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N-[(2S)-2-Pyrrolidinylmethyl]trifluoromethanesulfonamide features a chiral pyrrolidinylmethyl scaffold paired with a trifluoromethanesulfonyl group, delivering enhanced solubility and stability in polar solvents. This configuration enables efficient incorporation into complex molecular architectures, particularly in medicinal chemistry campaigns requiring robust amine protection or activation strategies.
N-[(2S)-2-Pyrrolidinylmethyl]trifluoromethanesulfonamide serves as a versatile chiral sulfonamide building block, enabling efficient access to enantioselective transformations. Its trifluoromethanesulfonyl group provides high electrophilicity and stability under standard reaction conditions, facilitating coupling with nucleophiles in amide bond formation and catalytic cross-coupling processes. The (2S)-pyrrolidinylmethyl moiety imparts conformational rigidity and favorable solubility, enhancing utility in medicinal chemistry synthesis and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3263
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: