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Structure of 801282-00-8
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2-Fluoro-3-methoxyaniline features a fluorine atom at the ortho position and a methoxy group at the meta position relative to the amine, creating a uniquely polarized aromatic scaffold. This electronic asymmetry enhances reactivity in cross-coupling processes and improves solubility in polar organic media. The molecule exhibits bench-stable handling under standard conditions and serves as a key intermediate for bioactive heterocycles and functional materials.
2-Fluoro-3-methoxyaniline serves as a versatile building block for pharmaceutical intermediates and agrochemicals, enabling efficient access to substituted heterocycles via standard coupling reactions. Its ortho-fluoro and meta-methoxy substituents provide balanced electronic modulation and enhanced stability under typical synthetic conditions, facilitating direct functionalization and minimizing side reactions. The compound exhibits excellent bench stability and is amenable to purification by distillation or chromatography, making it well-suited for scalable process development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: