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Structure of 80500-28-3
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4-Borono-2-nitrobenzoic acid features a boronate moiety paired with a nitro group and carboxylic acid functionality, enabling selective conjugation in bioorthogonal reactions. The electron-deficient aromatic core enhances reactivity in transition-metal-catalyzed coupling processes. This bench-stable derivative offers high solubility in aqueous and polar organic solvents, facilitating integration into synthetic workflows for probe development and targeted labeling.
4-Borono-2-nitrobenzoic acid serves as a versatile building block for the synthesis of boron-containing heterocycles and bioactive molecules. Its ortho-nitro and carboxylic acid functionalities enable directed metalation and selective functionalization, while the boronic acid group facilitates Suzuki-Miyaura coupling under mild conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthetic sequences in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: