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Structure of 947533-96-2
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This boronic acid features a sterically hindered aryl group with a trifluoromethyl substituent, enhancing stability and solubility in organic media. The electron-deficient ring facilitates efficient Suzuki-Miyaura coupling under standard conditions, enabling reliable C–C bond formation in complex molecule synthesis.
(2-Methyl-5-(trifluoromethyl)phenyl)boronic acid is a stable, bench-ready boronic acid that facilitates Suzuki-Miyaura cross-coupling reactions with high efficiency. It serves as a valuable building block for constructing biaryl scaffolds in medicinal chemistry and materials science, offering excellent functional group tolerance and ease of purification. Its trifluoromethyl and methyl substituents enhance metabolic stability and lipophilicity, making it particularly useful in the synthesis of advanced API intermediates and heterocyclic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: