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Structure of 81278-86-6
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5,8-Dibromoquinoline is a brominated quinoline derivative featuring two bromine atoms at the 5 and 8 positions, conferring enhanced electrophilicity and stability. This electron-deficient scaffold integrates readily into transition metal-catalyzed cross-coupling reactions, serving as a key building block in synthetic organic chemistry and medicinal research.
5,8-Dibromoquinoline serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established halogen reactivity. The dibrominated quinoline core exhibits excellent bench stability and facilitates orthogonal functionalization in heterocyclic scaffold development. Its defined substitution pattern supports predictable regiochemistry in C–C and C–heteroatom bond formation, making it particularly valuable for medicinal chemistry campaigns requiring precise molecular architecture.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: