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Structure of 81542-54-3
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5-Cyclohexyl-1H-pyrazol-3-amine features a sterically hindered pyrazole core bearing a cyclohexyl substituent at the 5-position and a primary amine at the 3-position. This scaffold delivers enhanced lipophilicity and metabolic stability, enabling efficient integration into bioactive molecules for medicinal chemistry applications.
5-Cyclohexyl-1H-pyrazol-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-based scaffolds with enhanced lipophilicity and metabolic stability. The amine functionality facilitates direct derivatization via acylation, alkylation, or coupling reactions, while the cyclohexyl group provides steric bulk and improved pharmacokinetic properties. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses targeting bioactive heterocycles.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: