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Structure of 827614-66-4
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1-Isobutyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole features a boronate ester group paired with a sterically hindered isobutylpyrazole scaffold. This combination enables stable coupling in Suzuki-Miyaura reactions under standard conditions, offering efficient access to functionalized heterocycles in medicinal chemistry and materials synthesis.
1-Isobutyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides metabolic stability and tunable polarity, while the pinacol boronate ester enables efficient coupling under mild conditions. Bench-stable and compatible with diverse functional groups, it facilitates rapid assembly of biaryl and heteroaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319
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Precautionary Statements : P210-P302+P352
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Lot numbers can be found on the outside label of a product: