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Structure of 910462-31-6
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tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate is a bench-stable boronate ester featuring a pyridine scaffold with a protected amine. This reagent enables efficient Suzuki-Miyaura coupling under mild conditions, combining high functional group tolerance with ease of handling. The tetramethyl-dioxaborolane moiety ensures stability and low toxicity, while the tert-butyl carbamate group provides orthogonal protection for nitrogen-based transformations.
tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate serves as a stable, bench-ready boron building block for palladium-catalyzed cross-coupling reactions. The pyridine core enables versatile functionalization in medicinal chemistry and materials science, while the Bpin group facilitates efficient Suzuki-Miyaura coupling under mild conditions. The tert-butyl carbamate protects the amine selectively, offering orthogonal handling and ease of removal post-coupling. This reagent exhibits excellent functional group tolerance and reproducible yields in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: