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Structure of 82998-57-0
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3-Iodo-4-methylbenzoic acid features a para-substituted aromatic core with iodine and methyl groups flanking a carboxylic acid moiety. This configuration enables direct functionalization in cross-coupling reactions, while the electron-deficient aryl halide facilitates palladium-catalyzed transformations. The molecule exhibits robust stability under standard handling conditions and integrates readily into complex molecular architectures requiring precise substitution patterns.
3-Iodo-4-methylbenzoic acid serves as a versatile building block for Suzuki-Miyaura and Stille couplings, enabling efficient access to biaryl and heteroaryl scaffolds. The iodine handle provides high reactivity under standard palladium catalysis, while the carboxylic acid facilitates direct derivatization or salt formation. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: