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Structure of 83948-54-3
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tert-Butyl (5-bromopentyl)carbamate delivers a reactive bromide handle at the terminus of a flexible pentyl chain, enabling efficient coupling in nucleophilic substitution reactions. The tert-butyl carbamate group provides reliable protection for primary amines, removable under mild acidic conditions. This bifunctional architecture supports modular synthesis in peptide and small-molecule development.
tert-Butyl (5-bromopentyl)carbamate serves as a versatile protecting group for primary amines, enabling selective functionalization in complex molecule synthesis. The bromide moiety facilitates efficient coupling reactions, including Buchwald–Hartwig amination and nucleophilic substitution, while the tert-butyl carbamate group offers excellent bench stability and ease of removal under mild acidic conditions. Its compatibility with diverse reaction conditions makes it a practical choice for building blocks in medicinal chemistry and peptide modification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: