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Ethyl 2-amino-4-chlorothieno[2,3-d]pyrimidine-6-carboxylate

  • CAS No. 847560-46-7

  • Cat. No. CS-0096041
  • Molecule weight257.70
  • Purity≥98%
  • MDL No.MFCD18074287

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-amino-4-chlorothieno[2,3-d]pyrimidine-6-carboxylate|CS-0096041

Structure of 847560-46-7

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General Information

  • CAS No. 847560-46-7
  • Cat. No. CS-0096041
  • Purity ≥98%
  • MDL No. MFCD18074287
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈ClN₃O₂S
  • Molecular Weight 257.70
  • Synonym(s) Thieno[2,3-d]pyrimidine-6-carboxylic acid, 2-amino-4-chloro-, ethyl ester
  • SMILES O=C(C1=CC2=C(Cl)N=C(N)N=C2S1)OCC

Synthesis

  • Route1
    • In-stock
      2-Amino-4,6-dichloropyrimidine-5-carbaldehyde|CS-M1767
      5604-46-6
    • null|null
      623-51-8
    • ~79%
    • In-stock
      Ethyl 2-amino-4-chlorothieno[2,3-d]pyrimidine-6-carboxylate|CS-0096041
      847560-46-7

    References

    • Brough, Paul A.; Barril, Xavier; Borgognoni, Jenifer; Chene, Patrick; Davies, Nicholas G. M.; Davis, Ben; Drysdale, Martin J.; Dymock, Brian; Eccles, Suzanne A.; Garcia-Echeverria, Carlos; Fromont, Christophe; Hayes, Angela; Hubbard, Roderick E.; Jordan, Allan M.; Jensen, Michael Rugaard; Massey, Andrew; Merrett, Angela; Padfield, Antony; Parsons, Rachel; Radimerski, Thomas; Raynaud, Florence I.; Robertson, Alan; Roughley, Stephen D.; Schoepfer, Joseph; Simmonite, Heather; Sharp, Swee Y.; Surgenor, Allan; Valenti, Melanie; Walls, Steven; Webb, Paul; Wood, Mike; Workman, Paul; Wright, Lisa Journal of Medicinal Chemistry, 2009 , vol. 52, # 15 p. 4794 - 4809
  • Route2

    References

    • Journal of Heterocyclic Chemistry, , vol. 43, # 6 p. 1629 - 1633

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.1
  • LogP   2.1036
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   2

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