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Structure of 849996-80-1
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2-Chloroquinoline-6-carboxylic acid features a chlorine-substituted quinoline core with a carboxylic acid group at the 6-position, enabling direct conjugation or derivatization in synthetic routes. This scaffold combines electron-deficient aromatic character with a handle for amide formation, offering utility in medicinal chemistry and materials synthesis.
2-Chloroquinoline-6-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via amide bond formation or Suzuki-Miyaura coupling. The ortho-chloro and carboxylic acid functionalities provide complementary reactivity for late-stage diversification, with demonstrated stability under standard synthetic conditions and compatibility with common protecting group strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: