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Structure of 851386-45-3
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3,6-Difluoropicolinic acid is a fluorinated pyridine carboxylic acid featuring electron-withdrawing fluorine substituents at the 3- and 6-positions. This configuration enhances its electrophilicity and metabolic stability, making it a valuable building block for pharmaceutical intermediates and bioactive heterocycles. The molecule exhibits favorable solubility in polar organic solvents and maintains bench stability under standard conditions.
3,6-Difluoropicolinic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive molecules. Its dual fluorine substituents enhance metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates straightforward derivatization via amide coupling or esterification. The compound exhibits good bench stability and compatibility with standard synthetic protocols, making it a practical choice for API intermediate development and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: