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CS-W001157 4
Total: USD 88.00

Fmoc-NH-PEG4-alcohol

  • CAS No. 868594-41-6

  • Cat. No. CS-0119262
  • Purity≥97%
  • MDL No.MFCD31657165

*For research and further manufacturing use only, not for direct human use.

Fmoc-NH-PEG4-alcohol|CS-0119262

Structure of 868594-41-6

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General Information

  • CAS No. 868594-41-6
  • Cat. No. CS-0119262
  • Purity ≥97%
  • MDL No. MFCD31657165
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₉NO₆
  • Molecular Weight 415.48
  • Synonym(s) None
  • SMILES O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCO

Description

Fmoc-NH-PEG4-alcohol features a photolabile Fmoc group conjugated to a four-ethylene glycol spacer terminating in a primary alcohol. This structure enables orthogonal protection in peptide synthesis and facilitates purification via affinity capture or solid-phase extraction. The terminal hydroxyl supports further functionalization for bioconjugation applications.

Application

Fmoc-NH-PEG4-alcohol serves as a versatile bifunctional linker for peptide and oligonucleotide synthesis, combining the orthogonal protection of the Fmoc group with a terminal hydroxyl for further conjugation. The PEG4 spacer enhances solubility and reduces aggregation in solid-phase workflows. This reagent enables efficient coupling to amines and subsequent functionalization via the alcohol handle, offering reliable stability, ease of purification, and compatibility with standard deprotection protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   86.25
  • LogP   2.5672
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   13

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