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Structure of 869557-43-7
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2-Amino-3-bromo-5-fluoropyridine features a pyridine core functionalized with amino, bromo, and fluoro groups at strategic positions. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions and serves as a key scaffold for medicinal chemistry libraries. The combination of polar substituents enhances solubility and reactivity under standard conditions.
2-Amino-3-bromo-5-fluoropyridine serves as a versatile building block for the synthesis of functionalized pyridine derivatives. Its orthogonal reactivity enables selective Suzuki-Miyaura and Ullmann couplings, while the amino group facilitates electrophilic substitution or derivatization. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: