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Structure of 872607-89-1
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1-Methyl-1H-indazole-5-carbaldehyde features a conjugated aldehyde group positioned at the 5-position of a methyl-substituted indazole core. This electron-deficient carbonyl integrates readily into multistep syntheses, enabling efficient access to heterocyclic scaffolds via nucleophilic addition or condensation reactions under standard conditions.
1-Methyl-1H-indazole-5-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the indazole core. The aldehyde group facilitates efficient coupling reactions, including reductive amination and Grignard additions, while the methyl-substituted indazole scaffold offers enhanced metabolic stability and favorable pharmacophore properties. Bench-stable and readily purified by flash chromatography, it functions reliably in multistep syntheses of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: