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Structure of 873-42-7
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2-Amino-3,5-dichloropyrazine is a heterocyclic amine featuring two chlorine substituents at electron-deficient positions, enabling robust coupling in cross-coupling reactions. This bench-stable derivative integrates readily into pharmaceutical scaffolds and serves as a key intermediate for bioactive nitrogen-rich compounds.
2-Amino-3,5-dichloropyrazine serves as a versatile building block in medicinal chemistry and agrochemical synthesis. Its electron-deficient pyrazine core enables efficient cross-coupling reactions, while the amino and dichloro substituents offer orthogonal functionalization potential. The compound exhibits good bench stability and facilitates the construction of complex heterocyclic scaffolds through sequential substitution, making it valuable for rapid diversification in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: