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Structure of 873055-23-3
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5-Chloro-1H-indol-6-amine features a chlorine-substituted indole core with a primary amine at the C6 position, enabling direct functionalization in medicinal chemistry. The electron-deficient aromatic system enhances reactivity in cross-coupling processes, while the amine group facilitates conjugation and derivatization under mild conditions. This scaffold serves as a key building block for bioactive heterocycles.
5-Chloro-1H-indol-6-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position for the synthesis of indole-based scaffolds. Its chlorine substituent facilitates palladium-catalyzed cross-coupling reactions, while the primary amine group offers straightforward derivatization via acylation, alkylation, or reductive amination. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development and target-oriented discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: