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Structure of 873697-68-8
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3-Amino-2-fluorobenzonitrile features a strategically positioned amino group adjacent to a fluorine atom and nitrile functionality, enabling selective coupling in heterocyclic synthesis. This electron-deficient aromatic scaffold facilitates efficient transition-metal-catalyzed transformations under standard conditions, offering enhanced reactivity for pharmaceutical intermediates.
3-Amino-2-fluorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its ortho-fluoro and amino groups facilitate directed metalation and electrophilic substitution, while the nitrile group supports transformation into carboxamides or carboxylic acids. The compound exhibits good bench stability and compatibility with standard coupling reactions, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: