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Structure of 876710-49-5
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This oxazole carboxylic acid features a 3,4-dichlorophenyl substituent at the 5-position, imparting enhanced electron-withdrawing character and improved metabolic stability. The conjugated oxazole core facilitates efficient coupling in synthetic transformations, while the carboxylic acid group enables direct derivatization or salt formation for solubility optimization.
5-(3,4-Dichlorophenyl)-1,2-oxazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its oxazole core exhibits enhanced metabolic stability and favorable pharmacokinetic properties, while the 3,4-dichlorophenyl substituent provides strong electron-withdrawing character and improved target binding affinity. The carboxylic acid functionality facilitates direct coupling reactions, derivatization, or salt formation, supporting downstream synthetic applications in API development. Bench-stable and readily purified by recrystallization, it functions efficiently in standard amide bond formations and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: